Could Prolonged Usage of GPS Navigation Implemented in Augmented Reality Smart Glasses Affect Hippocampal Functional Connectivity?

Table 1

Functional connectivity of HPC in the baseline TEST session 1 (p-FDR, p < 0.0001). The baseline (before intervention) functional connectivity of the left (L) and right (R) hippocampus in all recruited participants. The ten strongest connections (p-FDR corr. p < 0.0001) are displayed (for complete report of all significant results of FDR corrected at p < 0.05 see Supplementary Table 1).

L Hippocampus			R Hippocampus
Seed	Analysed_Unit	Statistic	Seed	Analysed_Unit	Statistic
HPC_left	pPaHC_l	T(32)=11.51	HPC_right	pPaHC_r	T(32)=12.55
	Hippocampus_r	T(32)=11.37		Hippocampus_l	T(32)=11.37
	Ver45	T(32)=10.22		LG_l	T(32)=10.35
	LG_l	T(32)=9.64		TOFusC_l	T(32)=10.28
	Cereb45_l	T(32)=9.26		LG_r	T(32)=10.10
	Ver3	T(32)=8.62		Ver3	T(32)=10.06
	LG_r	T(32)=8.49		Amygdala_r	T(32)=9.93
	pPaHC_r	T(32)=8.25		Ver45	T(32)=9.87
	pTFusC_l	T(32)=8.16		Cereb45_l	T(32)=9.63
	Brain-Stem	T(32)=7.94		pPaHC_l	T(32)=9.46

pPaHC_l/r (parahippocampal gyrus, posterior division, left/right); LG_l/r (lingual gyrus, left/right); TOFusC_l (temporal occipital fusiform cortex, left); Ver3 (vermis 3); Ver45 (vermis 4-5); Cereb45_l (cerebellum 4-5, left); pTFusC_l (temporal fusiform cortex, posterior division, left).