Research Article

Could Prolonged Usage of GPS Navigation Implemented in Augmented Reality Smart Glasses Affect Hippocampal Functional Connectivity?

Table 2

Hippocampal intervention related FC changes (p<0.05, uncorr.). AR glasses intervention related functional connectivity changes of the right (R) and left (L) hippocampi (p<0.05, uncorr.) tested by random-effect second-level analysis.

L HippocampusR Hippocampus
SeedAnalysed_UnitStatisticp-uncCohen's dSeedAnalysed_UnitStatisticp-uncCohen's d

HPC_leftCereb3_rT(31)=-3.180.0031.142HPC_rightpTFusC_lT(31)=-3.490.0021.254
Brain-StemT(31)=-2.710.0110.973Cereb3_rT(31)=-3.310.0021.189
Ver45T(31)=-2.680.0120.963pPaHC_lT(31)=-3.180.0031.142
Cereb3_lT(31)=-2.640.0130.948aPaHC_lT(31)=-2.690.0110.966
pPaHC_rT(31)=-2.530.0170.909Cereb3_lT(31)=-2.620.0130.941
pITG_lT(31)=-2.350.0250.844Hippocampus_lT(31)=-2.080.0460.747
Amygdala_lT(31)=-2.150.0390.772
Cereb45_rT(31)=-2.150.0390.772
Hippocampus_rT(31)=-2.080.0460.747

pTFusC_l (temporal fusiform cortex, posterior division, left); Cereb3_r/l (cerebelum 3, right/left); Cereb45_r (cerebellum 4 and 5, right); pPaHC_r/ l (parahippocampal gyrus, posterior division, right/left); aPaHC_l (parahippocampal gyrus, anterior division, left); Ver45 (vermis 4 and 5); pITG_l (inferior temporal gyrus, posterior division, left).