Evaluation and Comparison of Three Types of Spray Dried Coprocessed Excipient Avicel® for Direct Compression

Table 4

Properties of tablets.

Measured value	CP [MPa]	Avicel CE 15	Avicel DG	Avicel HFE 102
UM [mg]	78
	130
	182
PD [g/cm^3]	78
	130
	182
He [mm]	78
	130
	182
Fr [%]	78	2.56	0.10	0.01
	130	0.58	0.03	0.07
	182	0.28	0.03	0.04
Di [min]	78
	130
	182		>60.0
[min]	78
	130
	182
[min]	78
	130
	182
WA [%]	78
	130
	182

CP: compression pressure; UM: uniformity of mass; PD: pycnometric density; He: height; Fr: friability; Di: disintegration; , : wetting time; WA: water absorption ratio.