Arginine supplementation had protective effect on maintaining the colonic wall of irradiated rats (maintaining the partial volume of the colonic epithelium, not the total volume of the wall).
L-Glutamine supplementation reduced the severity of infections by improving intestinal barrier function (e.g., potential difference and Isc ↑, junctional proteins expression ↑), and by reducing mucosal cytokine response (e.g., IL-1β, IL-6, and TGF-β ↓).
Dietary glutamine supplementation had beneficial effects on the clinical and biochemical parameters of colitis (e.g., changes in serum amino acids profile, NF-B activity ↓, PI3K-Akt signaling ↓).
Dietary glycine prevented TNBS- or DSS-induced colitis by inhibiting inflammatory cytokine and chemokine production (e.g., IL-1β, TNF-α, myeloperoxidase activities, cytokine-induced neutrophil chemoattractant, and macrophage inflammatory protein ↓).
Glycine supplementation had protective effect on maintaining the colonic wall of irradiated rats (maintaining the thickness of colonic wall and mucosal epithelium).