Optimization of the Cytotoxic Activity of Three Streptomyces Strains Isolated from Guaviare River Sediments (Colombia, South America)

Table 3

Determination of the carbon source that improved the cytotoxic percent at 100 ppm of the Streptomyces extract for prostate (PC3), lung (A549), and breast (MDA-MB-231) tumour lines. The results are expressed as an average ± standard deviation (n=3).

Cytotoxicity at 100 ppm
	73			386			519
	PC3	A549	MDA	PC3	A549	MDA	PC3	A549	MDA
Saccharose	90.07 ± 0.21	70.31± 3.15	65.96± 3.06	89.81± 0.5	75.11± 0.74	65.1± 3.61	88.71± 0.82	85.18± 0.18	59.18± 0.84
Glucose	89.39 ± 0.63	78.17± 2.54	63.27± 1.62	90.64± 0.56	80.69± 1.38	57.11± 2.03	89.10± 0.67	86.78± 2.86	66.17± 1.83
Maltose	89.05 ± 1.05	76.09± 0.89	57.86± 2.74	87.64± 1.86	72.28± 1.24	61.33± 1.07	89.70± 0.48	86.61± 4.87	59.27± 0.72
Xylose	89.97 ± 1.77	81.83± 4.76	65.69± 3.01	89.60± 0.57	83.18± 1.63	65.63± 2.32	91.12± 1.02	87.78± 1.26	74.76± 2.79
Starch	91.22 ± 0.08	83.90± 1.05	68.10± 1.24	88.93± 1.02	81.49± 0.38	64.35± 0.84	90.59± 0.22	87.79± 0.58	62.58± 0.67