Optimization of the Cytotoxic Activity of Three Streptomyces Strains Isolated from Guaviare River Sediments (Colombia, South America)

Table 4

Determination of the IC₅₀ using the best carbon and nitrogen sources in Streptomyces strains for prostate (PC3), lung (A549), and breast (MDA-MB-231) tumour lines. The results are expressed as an average ± standard deviation (n=3).

IC50
Isolate	PC3	A549	MDA-MB-231	Carbon source/ Nitrogen source
73	50.26± 2.54	26.16± 3.26	26.65± 0.86	Starch
	74.36± 1.05	69.13± 1.05	45.39± 3.06	Yeast Extract
386	11.18± 3.85	31.64± 1.45	68.57± 1.08	Xylose
	14.59± 2.82	16.35± 4.03	71.25± 1.72	Malt Extract
519	55.80± 2.96	48.58± 2.39	39.98± 3.27	Xylose
	68.43± 2.74	50.49± 3.64	41.23± 2.84	Malt Extract