Optimization of the Cytotoxic Activity of Three Streptomyces Strains Isolated from Guaviare River Sediments (Colombia, South America)

Table 5

Determination of the nitrogen source that improved the cytotoxic percent at 100 ppm of the Streptomyces extract for prostate (PC3), lung (A549), and breast (MDA-MB-231) tumour lines. The results are expressed as an average ± standard deviation (n=3).

Cytotoxicity at 100 ppm
	73			386			519
	PC3	A549	MDA	PC3	A549	MDA	PC3	A549	MDA
Yeast extract	75.86± 0.35	63.45± 0.65	75.78± 0.61	69.32± 0.28	23.18± 3.96	18.07± 2.70	70.9 ±0.92	37.86± 0.79	46.49 ±0.80
Malt extract	68.72± 0.4	22.50± 0.59	33.24± 0.03	86.76± 4.76	67.93± 5.72	54.46± 0.36	77.59± 1.2	49.13± 2.55	59.73 ±2.16
Meat extract	77.14± 1.5	33.69± 5.58	48.85± 0.02	72.93± 0.98	21.82± 0.85	29.77± 1.54	68.42± 0.56	40.91± 2.96	47.46 ±1.96
Peptone	71.12± 5.32	29.13± 5.93	37.59± 0.94	68.79± 3.92	28.56± 5.51	48.00± 0.98	64.92± 4.98	33.96± 4.81	33.96 ±2.83
Potassium nitrate	67.51± 3.75	16.07± 4.15	22.91± 1.87	66.39± 1.81	33.10± 1.93	37.28± 1.79	71.80± 3.74	31.18± 3.62	31.18 ±0.08