Pleurotus albidus Modulates Mitochondrial Metabolism Disrupted by Hyperglycaemia in EA.hy926 Endothelial Cells

Figure 2

Mitochondrial respiratory chain assessment and intracellular reactive oxygen species (ROS) generation by endothelial cells treated with normal glucose (NG) or high glucose (HG) plus P. albidus extract (PleExt). (a) Complex I activity. (b) Complex II activity. (c) Complex III activity. (d) ATP levels. (e) Intracellular ROS generation. Results are expressed as mean ± SD of at least three independent experiments. Different letters indicate significantly different values among the treatments according to the analysis of variance (ANOVA) and Tukey’s post hoc test. Statistical significance was determined at p < 0.05.

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