Exosomes in Severe Asthma: Update in Their Roles and Potential in Therapy

Figure 2

Exosomes are small membrane-enclosed vesicles containing mRNA and miRNA, lipids, and a vast array of different proteins depending on their cell of origin. Generally exosomes are enriched in some of generic proteins such as proteins involved in MVB formation, tetraspanins, and membrane transports as well as a number of cytosolic proteins. In addition some compounds associated with specific pathological condition have been identified in exosomes.