Degalactotigonin, a Steroidal Glycoside from Solanum nigrum, Induces Apoptosis and Cell Cycle Arrest via Inhibiting the EGFR Signaling Pathways in Pancreatic Cancer Cells
Effect of 1 on EGF-induced migration of PANC1 cells. PANC1 cells were treated with the indicated concentrations of 1 and then underwent a transwell invasion assay in the absence or presence of EGF (100 ng/mL) for 12 h. Representative images were shown (top). The graphs represented quantification of migrated PANC1 cells (bottom) and the mean ± SD of three independent experiments was expressed. P<0.05, P<0.01 versus EGF only treated control.