Research Article

Composition Analysis and Feature Selection of the Oral Microbiota Associated with Periodontal Disease

Table 4

Features with significant differences between healthy patients and patients with periodontitis. Correlation coefficients and p values were determined by Spearman’s rank correlation coefficient and KruskalWallis tests, respectively. Negative correlations indicated that the features were observed more often in patients with periodontitis than in healthy patients.

NoFeature (Species)Correlation coefficient

1Stomatobaculum sp._oral_taxon_373-0.7660297543.27E-11
2Desulfobulbus sp._oral_taxon_041-0.748770588.90E-11
3Peptoniphilaceae sp._oral_taxon_113-0.7234180563.73E-10
4Streptococcus sanguinis0.716846245.36E-10
5Mollicutes sp._oral_taxon_906-0.7093694168.08E-10
6Aggregatibacter actinomycetemcomitans-0.6866081982.74E-09
7Porphyromonas gingivalis-0.6839936853.15E-09
8Peptostreptococcaceae sp._oral_taxon_950-0.6814891643.59E-09
9Lachnospiraceae sp._oral_taxon_500-0.6703245466.43E-09
10Leptotrichia sp._oral_taxon_218-0.6666422317.77E-09
11Bosea vestrisii0.6654688028.26E-09
12Filifactor alocis-0.6567974731.29E-08
13Mycoplasma faucium-0.6413228412.79E-08
14Prevotella sp._oral_taxon_304-0.6385879763.20E-08
15Fretibacterium sp._oral_taxon_359-0.6322908254.36E-08
16Bergeyella sp._oral_taxon_3220.6309615244.65E-08
17Tannerella forsythia-0.6283467045.28E-08
18Peptostreptococcus indolicus-0.6265049985.77E-08
19Johnsonella sp._oral_taxon_166-0.6223963937.04E-08
20Peptostreptococcaceae [Eubacterium]_saphenum-0.6167356799.24E-08