Cytotoxic and Apoptotic Effects of Govaniadine Isolated from Corydalis govaniana Wall. Roots on Human Breast Cancer (MCF-7) Cells

Figure 4

Effects of govaniadine on the morphology of MCF-7 cells after 24 (a), 48 (b), and 72 (c) h of postincubation. A, A1, and A2 control cells (0.1% DMSO); B, B1, and B2 cells treated with 1 μM of govaniadine; C, C1, and C2 cells treated with 2 μM of govaniadine; D, D1, and D2 cells treated with 4 μM of govaniadine; E, E1, and E2 cells treated with 8 μM of govaniadine; F, F1, and F2 cells treated with 16 μM of govaniadine. The cells were examined under an Olympus CKX41SF inverted phase contrast microscope using a 20 X objective lens (magnification 200X). Scale bar: 100 μm.

(a)

(b)

(c)