Deletion of NAD(P)H Oxidase 2 Prevents Angiotensin II-Induced Skeletal Muscle Atrophy

Figure 4

AII-induced apoptosis in the skeletal muscle is not improved by Nox2 deletion. Representative high-power photomicrographs of skeletal muscle tissue sections stained with terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) and summary data of quantitative analysis of TUNEL-positive nuclei ((a), (b) for each group). Scale bar, 100 μm. Quantitative analysis of cleaved (activated) caspase-3 in skeletal muscle tissue from WT + V, KO + V, WT + AII, and KO + AII ((c) for each group). Data are expressed as means ± SEM. versus WT + V.

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