BioMed Research International / 2018 / Article / Fig 2

Research Article

Effect of Riociguat and Sildenafil on Right Heart Remodeling and Function in Pressure Overload Induced Model of Pulmonary Arterial Banding

Figure 2

Effects of sildenafil and riociguat and on RV cardiomyocyte size and collagen content after PAB. (a, b) Representative pictures and quantification of cardiomyocyte cross-sectional area based on a cell plasma membrane staining with wheat germ agglutinin- (WGA-) FITC (mean ± SD, 5 mice per group, ). Scale bar 100 μm. (c, d) Representative images and assessment of RV collagen area (%), representing reduced collagen content in riociguat-treated samples (mean ± SD, 5 mice per group, , ). Scale bar 100 μm.
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