Saccharomyces cerevisiae-Derived Mannan Does Not Alter Immune Responses to Aspergillus Allergens

Figure 4

Airways resistance was unaffected by MN treatment. While naïve and nonallergic mice that received MN had no airway hyperresponsiveness, those that were sensitized and challenged with allergen had increased airways resistance. MN-treated allergic animals had an equivalent response to methacholine as allergic mice that were not treated with MN. Data are represented as the mean and standard deviation in –10 mice per group. Data in each group were analyzed by two-way ANOVA with Tukey’s multiple comparisons test and denotes .