Research Article

High Mobility Group Box Protein 1 Serves as a Potential Prognostic Marker of Lung Cancer and Promotes Its Invasion and Metastasis by Matrix Metalloproteinase-2 in a Nuclear Factor-κB-Dependent Manner

Figure 2

High mobility group box protein 1 (HMCB1) promoted invasion of lung cancer cells. Pretreatment of HMGB1 significantly promoted invasion of A549 and H1299 cells.