Immunoglobulin E and G Levels in Predicting Minimal Change Disease before Renal Biopsy

Table 3

Univariate and multivariate logistic regression analyses of factors associated with minimal change disease.

Potential factors	Univariate		Multivariate
			Model 1		Model 2		Model 3
	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
Age, per year	0.92 (0.89-0.95)	<0.001	0.94 (0.90-0.98)	0.004	0.94 (0.91-0.98)	0.005	0.95 (0.91-0.99)	0.011
Sex (men)	2.59 (1.14-5.88)	0.02	0.58 (0.13-2.59)	0.48	0.79 (0.17-3.60)	0.76	0.51 (0.10-2.63)	0.47
Hemoglobin, per g/dl	1.81 (1.43-2.30)	<0.001	1.68 (1.10-2.57)	0.016	1.57 (1.06-2.33)	0.024	1.61 (1.05-2.47)	0.029
Proteinuria, per g/day	1.13 (1.06-1.20)	<0.001	1.04 (0.95-1.13)	0.40	1.05 (0.97-1.14)	0.22	1.00 (0.92-1.09)	0.95
IgG < 450 mg/dl	8.12 (3.29-20.1)	<0.001	4.29 (1.07-17.20)	0.04	-	-
IgE > 110 mg/dl	10.32 (2.90-36.7)	<0.001	-	-	9.14 (1.74-47.89)	0.009
Risk serology markers: IgG < 450 mg/dl, IgE > 110 mg/dl								0.02
1 versus 0 risk markers							7.34 (0.76-70.71)	0.085
2 versus 0 risk markers							31.84 (2.55-397.3)	0.007