C-Kit Cardiac Progenitor Cell Based Cell Sheet Improves Vascularization and Attenuates Cardiac Remodeling following Myocardial Infarction in Rats

Figure 6

Angiogenesis in left ventricle 14 days after myocardial infarction and CPC sheet delivery. (a) Representative images of capillaries and arterioles in border zone in control group and after cell sheet treatment. Two weeks after epicardial delivery of CPC sheets sections were costained with antibodies against endothelial marker CD31 (red) and smooth muscle marker-smooth muscle actin (green); nuclei are counterstained by DAPI (blue). (b) Bar graphs represent analysis of density for capillaries, vessels with lumen and arterioles in border zone. (c) Bar graphs graphs represent analysis of density for capillaries, vessels with lumen and arterioles in infarct zone. Data is presented as meanSD. p<0.05 versus control.

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