Biochanin A Induces S Phase Arrest and Apoptosis in Lung Cancer Cells

Figure 7

Biochanin A decreases mitochondrial membrane potential (ΔΨm) in A549 cells. Flow cytometric analysis of ΔΨm. A549 cells were treated with Biochanin A (0, 50, 100, and 200μmol/L) followed by rhodamine 123 staining. Cells with high ΔΨm are marked “survival” and those with low ΔΨm are marked “apoptosis”. Percentages (%) of cells with high ΔΨm (survival) and low ΔΨm (apoptosis) are shown. These results were from 1 representative experiment of 3 independent trials. Values represent the mean ± SD (n = 3). < 0.05; < 0.01; < 0.001.