Identification of Hub Genes and Key Pathways Associated with Two Subtypes of Diffuse Large B-Cell Lymphoma Based on Gene Expression Profiling via Integrated Bioinformatics

Table 4

Top 10 genes evaluated in the PPI network using five calculation methods (MCC, MNC, Degree, EPC, and EcCentricity) and employing CytoHubba in Cytoscape.

gene_name	MCC	Gene name	MNC	gene name	Degree	gene name	EPC	gene name	EcCentricity
IRF4	11	STAT3	6	IRF4	8	STAT3	10.782	STAT3	0.28571
STAT3	11	IRF4	5	STAT3	7	IRF4	10.659	IRF4	0.21429
CD44	8	CD44	5	CD44	5	CD44	10.346	CD44	0.21429
MME	6	MME	4	MME	4	IL2RA	9.487	IL2RA	0.21429
ETV6	4	ETV6	3	CCND2	4	MME	9.32	CCND2	0.21429
LMO2	4	IL2RA	3	CDK14	4	CCND2	9.148	CFLAR	0.21429
CCND2	4	CCND2	2	LMO2	4	CFLAR	8.598	BATF	0.21429
CDK14	4	CDK14	2	ETV6	3	BATF	8.404	NFKBIZ	0.21429
IL2RA	4	CFLAR	2	IL2RA	3	ETV6	8.374	MME	0.17143
CFLAR	3	HOPX	2	CFLAR	3	HOPX	7.399	ETV6	0.17143