Research Article

Identification of Hub Genes and Key Pathways Associated with Two Subtypes of Diffuse Large B-Cell Lymphoma Based on Gene Expression Profiling via Integrated Bioinformatics

Table 5

GO analysis and pathway enrichment for hub gene functions.

TermDescriptionCountFalse discovery rateGenes

Biological Process

GO.0071345cellular response to cytokine stimulus50.00579CD44, IL2RA, IRF4,
MME, STAT3

GO.0014842regulation of satellite cell proliferation20.0218CFLAR, STAT3

GO.0019221cytokine-mediated signaling pathway40.0218CD44, IL2RA, IRF4,
STAT3

Pathway

4640Hematopoietic cell lineage30.0011CD44, IL2RA, MME

4630JAK-STAT signaling pathway30.00164CCND2, IL2RA,
STAT3

5162Measles30.00164CCND2, IL2RA,
STAT3

5206MicroRNAs in cancer30.00164CCND2,CD44,STAT3

4917Prolactin signaling pathway20.0178CCND2,STAT3

4068FOXO signaling pathway20.0447CCND2,STAT3