A Comparison of Traditional and Novel Methods for the Separation of Exosomes from Human Samples

Figure 2

Schematic of an integrated double filtration microfluidic device for separation exosomes. Based on size-exclusion, particles larger than 200 nm are excluded by the membrane with a pore size of 200 nm in the sample chamber, whereas those smaller than 30 nm pass through the device into the waste chamber. Exosomes with a size between 30 and 200 nm are separated and enriched in the isolation chamber.