Biatrial versus Isolated Left Atrial Ablation in Atrial Fibrillation: A Systematic Review and Meta-Analysis

Table 4

Sensitivity and subgroup analyses.

Endpoint	Restored SR at discharge		Restored SR at 12 months		Restored SR beyond 1 year
	Overall value	OR (95% CI)	Overall value	OR (95% CI)	Overall value	OR (95% CI)
Study design					0.46	1.37 (0.60, 3.11)
RCT	0.38	0.51 (0.12, 2.25)	Have no RCT studies		0.69	1.25 (0.43, 3.65)
Non-RCT	0.4	1.17 (0.81, 1.68)
Study size
<150	0.88	1.05 (0.56, 1.95)	0.04	1.76 (1.02, 3.04)	0.76	1.22 (0.24, 4.46)
>150	0.96	0.99 (0.66, 1.49)	0.44	1.29 (0.67, 2.48)	0.3	1.44 (0.73, 2.85)
Statistical models
Fixed-effect	0.3	1.12 (0.90, 1.38)	0.009	1.39 (1.09, 1.79)	0.16	1.21 (0.92, 1.59)
Random-effect	0.34	1.15 (0.86, 1.55)	0.2	1.37 (0.85, 2.21)	0.4	1.31 (0.70, 2.48)

SR: sinus rhythm; RCT: randomized, controlled trial.