The Transcription Factor ATF4 Promotes Expression of Cell Stress Genes and Cardiomyocyte Death in a Cellular Model of Atrial Fibrillation

Table 2

Patient characteristics.

Patient #	Rhythm	Age	Sex	Surgical treatment	CHD	CM	LA dilatation	aortic valve stenosis	mitral valve insufficiency
1	SR	58	m	aortic valve replacement and coronary bypass grafting				X
2	SR	57	m	aortic valve replacement and coronary bypass grafting	X			X
3	SR	56	m	acute mitral valve endocarditis; mitral valve replacement			X		X
4	SR	74	f	aortic valve and mitral valve replacement			X	X	X
5	SR	53	m	aortic valve replacement		DCM		X
6	SR	74	f	coronary bypass grafting	X	ICM	X
7	SR	78	m	aortic valve replacement				X
8	SR	57	m	aortic valve replacement				X
9	SR	79	m	aortic valve replacement and coronary bypass grafting	X			X
10	AF	77	f	aortic valve replacement and coronary bypass grafting	X			X
11	AF	81	m	aortic valve replacement			X	X
12	AF	81	m	aortic valve replacement		DCM	X	X
13	AF	58	m	mitral valve reconstruction			X		X
14	AF	73	m	aortic valve replacement and mitral valve reconstruction			X	X	X
15	AF	66	f	aortic valve replacement		DCM	X	X
16	AF	68	m	aortic valve replacement and coronary bypass grafting	X	ICM	X	X
17	AF	77	m	aortic valve replacement				X
18	AF	75	m	aortic valve replacement and mitral valve and tricuspid valve reconstruction	X	ICM		X	X

List of 17 patients undergoing cardiac surgery (SR: sinus rhythm, AF: atrial fibrillation, CHD: coronary heart disease, CM: cardiomyopathy, DCM: dilated cardiomyopathy, ICM: ischemic cardiomyopathy, and LA: left atrium).