BioMed Research International

Research Article

Mutational Profile of Metastatic Breast Cancer Tissue in Patients Treated with Exemestane Plus Everolimus

Table 2

Mutations detected in relapse tissue and in primary breast cancer.
  Relapse mutationsPrimary tumor mutations
  statusgenemutationstatusgenemutation
Patient 1wild type  not available   
Patient 2mutatedBRAFR444Wnot available   
Patient 3wild type  not available   
Patient 4wild type  not available   
Patient 5wild type  not available   
Patient 6mutatedPIK3CA AKT1E545K E17Knot available   
Patient 7not available  mutated FBX4 PIK3CA KITG30N E545K S709F
Patient 8wild type  not available   
Patient 9mutatedTP53R273Hwild type  
Patient 10wild type  mutated AKT1E17K
Patient 11wild type  wild type  
Patient 12wild type  not available   
Patient 13wild type  mutated AKT1E17K
Patient 14wild type  not available   
Patient 15mutatedKITG565Rnot available   
Patient 16wild type  wild type  
Patient 17not available  wild type  
Patient 18mutatedFBXW7R479Qmutated MAP2K1D67N
Patient 19wild type  wild type  
Patient 20mutatedCTNNB1S45Fwild type  
Patient 21not available  wild type  
Patient 22not available  mutated FBXW7R465C
Patient 23wild type  not available   
Patient 24not available  wild type  
Patient 25wild type  not available