Clinical Study

Reducing Blood Loss in Revision Total Hip and Knee Arthroplasty: Tranexamic Acid Is Effective in Aseptic Revisions and in Second-Stage Reimplantations for Periprosthetic Infection

Table 1

Demographic data and preoperative blood variables. Given are mean values (SD), except the absolute amounts for female gender.

Demographic dataTXA
Revision THA n=96
Revision TKA n=51
No TXA
Revision THA n=103
Revision TKA n=52
p-value

Age [years]
 Revision THA66.1 (13.5)68.6 (11.3)0.16
 Revision TKA65.3 (15.2)66.1 (12.4)0.78
Female gender, N (%)
 Revision THA57 (59%)56 (54%)0.48
 Revision TKA26 (51%)28 (54%)0.77
Height [m]
 Revision THA1.69 (0.11)1.69 (0.10)0.68
 Revision TKA1.70 (0.10)1.69 (0.11)0.57
Weight [kg]
 Revision THA76.6 (16.1)77.6 (18.6)0.69
 Revision TKA85.2 (21.2)88.0 (22.3)0.51
Calculated blood volume [ml]
 Revision THA4943 (870)4865 (877)0.86
 Revision TKA5205 (948)5265 (1070)0.77
ASA score
 Revision THA2.52 (0.78)2.48 (0.58)0.65
 Revision TKA2.47 (0.64)2.44 (0.57)0.81
Preoperative Ht
 Revision THA0.386 (0.051)0.388 (0.047)0.71
 Revision TKA0.391 (0.053)0.391 (0.041)0.97
INR preop.
 Revision THA1.01 (0.07)1.01 (0.07)0.51
 Revision TKA1.01 (0.06)1.01 (0.06)0.71

TXA, tranexamic acid; THA, total hip arthroplasty; TKA, total knee arthroplasty; ASA, American Society of Anesthesiologists; Ht, hematocrit; INR, international normalized ratio; SD, standard deviation; Welch’s test