Reducing Blood Loss in Revision Total Hip and Knee Arthroplasty: Tranexamic Acid Is Effective in Aseptic Revisions and in Second-Stage Reimplantations for Periprosthetic Infection
Table 1
Demographic data and preoperative blood variables. Given are mean values (SD), except the absolute amounts for female gender.
Demographic data
TXA Revision THA n=96 Revision TKA n=51
No TXA Revision THA n=103 Revision TKA n=52
p-value
Age [years]
Revision THA
66.1 (13.5)
68.6 (11.3)
0.16†
Revision TKA
65.3 (15.2)
66.1 (12.4)
0.78
Female gender, N (%)
Revision THA
57 (59%)
56 (54%)
0.48
Revision TKA
26 (51%)
28 (54%)
0.77
Height [m]
Revision THA
1.69 (0.11)
1.69 (0.10)
0.68
Revision TKA
1.70 (0.10)
1.69 (0.11)
0.57
Weight [kg]
Revision THA
76.6 (16.1)
77.6 (18.6)
0.69
Revision TKA
85.2 (21.2)
88.0 (22.3)
0.51
Calculated blood volume [ml]
Revision THA
4943 (870)
4865 (877)
0.86
Revision TKA
5205 (948)
5265 (1070)
0.77
ASA score
Revision THA
2.52 (0.78)
2.48 (0.58)
0.65†
Revision TKA
2.47 (0.64)
2.44 (0.57)
0.81
Preoperative Ht
Revision THA
0.386 (0.051)
0.388 (0.047)
0.71
Revision TKA
0.391 (0.053)
0.391 (0.041)
0.97
INR preop.
Revision THA
1.01 (0.07)
1.01 (0.07)
0.51
Revision TKA
1.01 (0.06)
1.01 (0.06)
0.71
TXA, tranexamic acid; THA, total hip arthroplasty; TKA, total knee arthroplasty; ASA, American Society of Anesthesiologists; Ht, hematocrit; INR, international normalized ratio; SD, standard deviation; †Welch’s test