Reducing Blood Loss in Revision Total Hip and Knee Arthroplasty: Tranexamic Acid Is Effective in Aseptic Revisions and in Second-Stage Reimplantations for Periprosthetic Infection
Table 4
Main outcome variables of the subgroup analysis between aseptic revisions. Given are the mean values (SD), in addition to minimum, maximum, and median for surgical time.
Outcome variables
TXA aseptic rTHA n=75 aseptic rTKA n=30
No TXA aseptic rTHA n=85 aseptic rTKA n=25
p-value
Aseptic rTHA
Surgical time [min]
151.1 (52.7)
140.0 (50.6)
0.1790†
Min; Max; Median
50; 290; 150
60; 270; 125
Ht POD 5
0.290 (0.031)
0.280 (0.029)
0.0453
RBC transfused total [unit]
1.19 (1.39)
1.73 (1.74)
0.0320
Transfusion rate
0.51 (0.50)
0.61 (0.49)
0.1833
Calc. blood loss [ml]
2740 (1220)
3342 (1304)
0.0031
Complication rate
0.24 (0.43)
0.12 (0.33)
0.0550†
Aseptic rTKA
Surgical time [min]
163.0 (38.9)
169.0 (46.8)
0.6056
Min; Max; Median
105; 260; 150
120; 255; 165
Ht POD 5
0.295(0.038)
0.276 (0.025)
0.0290†
RBC transfused total [unit]
1.03 (1.73)
1.20 (1.58)
0.7132
Transfusion rate
0.37 (0.49)
0.48 (0.51)
0.4056
Calc. blood loss [ml]
2411 (979)
3053 (957)
0.0178
Complication rate
0.25 (0.44)
0.25 (0.44)
1.0000
TXA, tranexamic acid; rTHA, revision total hip arthroplasty; rTKA, revision total knee arthroplasty; POD, postoperative day; Ht, hematocrit; INR, international normalized ratio; RBC, packed red blood cells; DVT, deep vein thrombosis; PE, pulmonal embolism; : significant; †: Welch’s test.
