Reducing Blood Loss in Revision Total Hip and Knee Arthroplasty: Tranexamic Acid Is Effective in Aseptic Revisions and in Second-Stage Reimplantations for Periprosthetic Infection
Table 5
Main outcome variables of the subgroup analysis between reimplantations. Given are the mean values (SD), in addition to minimum, maximum, and median for surgical time.
No TXA Reimplantation THA n=18 Reimplantation TKA n=27
p-value
Reimplantation THA
Surgical time [min]
157.9 (48.1)
196.9 (94.1)
0.1239
Min; Max; Median
90; 290; 150
110; 420; 175
Ht POD 5
0.280 (0.023)
0.268 (0.029)
0.1964
RBC transfused total [unit]
2.57 (1.91)
3.33 (2.22)
0.2571
Transfusion rate
0.81 (0.40)
0.83 (0.38)
0.8517
Calc. blood loss [ml]
3544 (1052)
4882 (1604)
0.0035
Complication rate
0.10 (0.31)
0.28 (0.46)
0.1173†
Reimplantation TKA
Surgical time [min]
192.4 (44.9)
178.6 (59.5)
0.3804
Min; Max; Median
130; 300; 180
120; 360; 160
Ht POD 5
0.256 (0.020)
0.271 (0.025)
0.0273
RBC transfused total [unit]
1.38 (1.32)
1.85 (1.70)
0.3015
Transfusion rate
0.62 (0.50)
0.67 (0.48)
0.7388
Calc. blood loss [ml]
3249 (744)
3801 (1117)
0.0464†
Complication rate
0.21 (0.41)
0.33 (0.48)
0.3846
TXA, tranexamic acid; THA, total hip arthroplasty; TKA, total knee arthroplasty; ASA, American Society of Anesthesiologists; Ht, hematocrit; INR, international normalized ratio; SD, standard deviation; †Welch’s test.
