A Network Pharmacology Analysis to Explore the Effect of Astragali Radix-Radix Angelica Sinensis on Traumatic Brain Injury

Figure 2

A network analysis of AR-RAS. (a) The compound-putative protein network is constructed by linking the 19 candidate compounds and their putative 226 target proteins. The nodes represent candidate compounds in AR-RAS which are shown as purple oval, and the targets are indicated by green fusiform (245 nodes and 517 edges). (b) Gene Ontology (GO) analysis of targets. Top 5 significantly enrichment terms in Biological Process (BP), Cellular Component (CC), and Molecular Function (MF). Longitudinal-axis shows target proteins significantly enrich in Biological Process, Cellular Component, and Molecular Function categories of the targets, and the horizontal-axis shows the enrichment score of these terms (-Log10(P)). The blue bar represents Biological Process, red bar represents Molecular Function, and yellow bar represents Cellular Component. (c) Compound-pathway network. Blue hexagon: a compound of AR-RAS and red and yellow circles: target pathway. Edge: interaction between a target and a pathway.

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