An Evaluation of Clinical and Histopathological Aspects of Patients with Oral Submucous Fibrosis in the Background of Oral Squamous Cell Carcinoma

Table 1

Summary of the results.

	Patients with OSF+OSCC	Patients with OSCC	P value
Age	31 patients <50 years	33 patients < 50 years
	99 patients > 51 years	110 patients >51 years
Sex	M: F	M:F
	3.2:1	2.3:1
Habits
Betel quid chewing	99	23	<0.05
Quid with alcohol or smoking	13	10
Alcohol and smoking	0	5
All 3 habits	22	9
Primary site
Commissure	1	7
Buccal mucosa	47	51
Floor of the mouth	9	10
Tongue	39	38
Alveolar ridge (upper and lower)	30	33
Lip	2	1
Palate	0	5
Degree of fibrosis and Histological differentiation
Early fibrosis:
EISCC	02	02	P=0.195
WDSCC	32	91
MDSCC	15	42
PDSCC	05	06
Intermediate fibrosis:
EISCC	03
WDSCC	23
MDSCC	16
PDSCC	01
Advanced fibrosis:
EISCC	01
WDSCC	16
MDSCC	14
PDSCC	02
Lymph node metastasis	24 (22.6%)	29 (30.8%)	P=1.89

Significant association between betel quid and OSF P<0.05, EISCC- early invasive SCC, WDSCC-well DSCC, MDSCC- moderately DSCC, PDSCC- poorly DSCC (DSCC-differentiated squamous cell carcinoma).