Propofol Reversed Hypoxia-Induced Docetaxel Resistance in Prostate Cancer Cells by Preventing Epithelial–Mesenchymal Transition by Inhibiting Hypoxia-Inducible Factor 1<i>α</i>

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left" rowspan="2">Cell lines</td><td class="align_center" colspan="3">HIF-1<i>α</i>/<i>β</i>-actin</td></tr><tr class="thead"><td class="align_center">Normoxic</td><td class="align_center">Hypoxic</td><td class="align_center">Hypoxic + Propofol</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">PC3</td><td class="align_center">0.448049</td><td class="align_center">0.942486</td><td class="align_center">0.508608</td></tr><tr><td class="align_left">DU145</td><td class="align_center">0.420623</td><td class="align_center">1.034483</td><td class="align_center">0.698514</td></tr><tr><td class="align_left">22RV1</td><td class="align_center">0.439184</td><td class="align_center">1.303041</td><td class="align_center">0.549622</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

The grey value of the HIF-1<i>α</i> protein treated with or without propofol under normoxia or hypoxia conditions.

BioMed Research International

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Table 3

Table 3: Propofol Reversed Hypoxia-Induced Docetaxel Resistance in Prostate Cancer Cells by Preventing Epithelial–Mesenchymal Transition by Inhibiting Hypoxia-Inducible Factor 1<i>α</i> 

Table 3 | Propofol Reversed Hypoxia-Induced Docetaxel Resistance in Prostate Cancer Cells by Preventing Epithelial–Mesenchymal Transition by Inhibiting Hypoxia-Inducible Factor 1α 