Circulating MicroRNA-4739 May Be a Potential Biomarker of Critical Limb Ischemia in Patients with Diabetes

Figure 3

ROC curve analysis of miRNA-4739 cut point for the presence of CLI in T2DM patients. The AUC of miRNA-4739 was 0.69 (P< 0.05); identified miR-4739 cut point was 0.42, Youden index = 0.35; sensitivity: 61.54%; specificity: 73.33%. The AUC of confounding risk factors and miRNA-4739+ confounding risk factors were 0.91 and 0.94, respectively (P< 0.001).