Circulating MicroRNA-4739 May Be a Potential Biomarker of Critical Limb Ischemia in Patients with Diabetes

Table 4

Binary logistic regression analysis for the risk factors of CLI in T2DM patients.

	OR	95% CI for OR	P		95% CI for
T2D Duration	1.189	1.051-1.345	0.006
Hypertension	3.182	1.057-9.581	0.040
Smoking	3.750	1.220-11.523	0.021
FPG	1.377	1.117-1.698	0.003
HbA1c	1.730	1.168-2.563	0.006
TC	0.550	0.338-0.897	0.017
Cr	1.019	1.000-1.038	0.049
miRNA-4739	6.610	1.615-27.054	0.009	12.818	1.148-143.143	0.038

CI, confidence interval; FPG, fasting plasma glucose; HbA1c, glycosylated hemoglobin; TC, total cholesterol; Cr, serum creatinine. Adjusted for T2D duration, hypertension, smoking, FPG, HbA1c, TC, and Cr. All study subjects were included in the analysis. Significant values are marked in italic.