Candidate Biomarkers and Molecular Mechanism Investigation for Glioblastoma Multiforme Utilizing WGCNA

Figure 1

The heat map, volcano plot, and weighted gene coexpression network analysis (WGCNA) of differentially expressed genes (DEGs) between glioblastoma multiforme group and control group. (a) The heat map for DEGs. (b) The volcano plot for DEGs. Grey dots represent genes which are not differentially expressed, red dots represent the upregulated genes, and the blue dots represent the downregulated genes. (c) Determination of the soft threshold in the WGCNA algorithm. The approximate scale-free fit index can be attained at the soft-thresholding power of 18. (d) Clustering dendrograms showing 5 modules that contain a group of highly connected genes. Each designated color represents a certain gene module.

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