Research Article

Association between Insulin-Like Growth Factor-1 and Uric Acid in Chinese Children and Adolescents with Idiopathic Short Stature: A Cross-Sectional Study

Table 1

Demographic characteristics and biochemical values of the subjects.

Variables All

Number91
Sex (male , %)68 (74.7%)
Age (years) 10.1 ± 3.8
SBP (mmHg) 107.3 ± 12.5
DBP (mmHg) 63.9 ± 10.1
Height (cm) 126.3 ± 20.0
Body weight (kg) 27.6 ± 10.9
BMI (kg/m2) 16.56 ± 2.21
IGF-1 (ng/ml) 210.08 ± 148.89
IGF-1 SDS −0.65 ± 1.19
IGFBP-3 (μg/ml) 4.74 ± 1.35
Cr (μmol/L) 38.70 ± 10.93
BUN (μmol/L) 4.86 ± 3.13
UA (μmol/L) 271.39 ± 70.28
TC (mmol/L) 3.64 ± 0.69
TG (mmol/L) 0.58 (0.48–0.86)
HDL-C (mmol/L)1.32 ± 0.26
LDL-C (mmol/L) 1.92 ± 0.51
VLDL-C (mmol/L) 0.40 ± 0.20
ALT (U/L) 14.00 (12.00–17.30)
AST (U/L) 25.92 ± 5.34
GGT (U/L) 11.91 ± 2.55
FPG (mmol/L) 4.55 ± 0.41
Pubertal stage
 In prepuberty (, %)67 (73.6%)
 In puberty (, %)24 (26.4%)

SBP: systolic blood pressure; DBP: diastolic blood pressure; BMI: body mass index; IGF-1: insulin-like growth factor-1; IGF-1 SDS: the standard deviation score of IGF-1; IGFBP-3: insulin-like growth factor-binding protein-3; Cr: creatinine; BUN: blood urea nitrogen; UA: uric acid; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; VLDL-C: very low-density lipoprotein cholesterol; ALT: alanine aminotransferase; AST: aspartate transaminase; GGT: gamma-glutamyl transferase; FPG: fasting plasma glucose. Normal distribution of data was presented as mean ± standard deviation; nonnormal distribution of data was presented as median (interquartile range) and was log-transformed (base 10) before parametric tests; the categorical data was expressed by the numbers and percentage (, %).