Research Article

Fibrosis-4 Model Influences Results of Patients with Hepatocellular Carcinoma Undergoing Hepatectomy

Table 1

Characteristics of the included patients.

ParametersN(%)

Male668 (84.8%)
Age (years) (Mean ± SD)51.1±11.9
Etiology
 HBV665 (84.4%)
 HCV14 (1.8%)
 NBNC109 (13.8%)
Child-Pugh Score
 A746 (94.7%)
 B42 (5.3%)

MELD, median (IQR)8 (7-10)
AST (U/L) (Mean ± SD)51.1±38.6
ALT (U/L) (Mean ± SD)49.8±40.6
Total bilirubin (umol/L) (Mean ± SD)16.2±13.7
Albumin (g/L) (Mean ± SD)41.2±4.4
INR (Mean ± SD)1.27±0.15
PLT (109/L) (Mean ± SD)140±70
Ishak
 0-2282 (35.8%)
 3-495 (12.1%)
 5-6411 (52.2%)
Cirrhosis411 (52.2%)
AFP (ng/mL) (Mean ± SD)10 (7.4%)
BCLC
 0-A537 (68.2%)
 B117 (14.8%)
 C134 (17.0%)
Tumor
  Single636 (80.7%)
 Multiple152 (19.3%)
Macrovascular invasion93 (11.8%)
Microvascular Invasive162 (20.6%)
Differentiation Degree
 Poor89 (11.3%)
 Moderate680 (86.3%)
 Well19 (2.4%)
Recurrent Hepatocellular Carcinoma37 (4.7%)
Complications III-V68 (8.6%)
Transfusion175 (22.2%)
Hospital Stay (days) median (IQR)9 (7-11)
AST/ALT (Mean ± SD)1.2±1.0
APRI (Mean ± SD)1.2±1.7
FIB-4 (Mean ± SD)3.6±3.7
Lok (Mean ± SD)12.6±1.6
King Score (Mean ± SD)33.1±43.7

ALT: alanine aminotransferase; AST: aspartate aminotransferase. AFP: α-fetoprotein; BCLC: Barcelona Clinic Liver Cancer; INR: international normalized ratio; PLT: platelet count. APRI: AST-to-platelet ratio Index; HBV: hepatitis B virus; HCV: hepatitis C virus; NBNC: non-B non-C hepatitis virus. MELD: model for end-stage liver disease; IQR: interquartile range; SD: standard deviation.