Effect of Neoadjuvant Hormone Therapy on Resection Margin and Survival Prognoses in Locally Advanced Prostate Cancer after Prostatectomy Using Propensity-Score Matching

Table 2

Logistic regression model for resection margin positivity before and after propensity score matching.

Variables	Before propensity score matching				After propensity score matching
	Univariable analysis		Multivariable analysis		Univariable analysis
	OR (95% CI)	p value	OR (95% CI)	p value	OR (95% CI)	p value
NHT plus RRP versus RRP alone	0.43 (0.22-0.86)	0.016	0.59 (0.27-1.30)	0.188	0.46 (0.19-1.11)	0.084
Age ≥65	0.82 (0.42-1.60)	0.561			0.73 (0.30-1.74)	0.473
PSA ≥40	1.41 (0.71-2.79)	0.328			4.23 (1.64-10.93)	0.003
Biopsy Gleason score sum ≥7	1.47 (0.56-3.91)	0.436			1.86 (0.49-7.15)	0.365
Tumor volume ≥50%	6.67 (3.26-13.62)	<.001	3.68 (1.67-8.09)	0.001	5.78 (2.28-14.63)	<.001
Extracapsular extension	9.33 (4.04-21.53)	<.001	5.26 (2.13-12.96)	<.001	6.29 (2.16-18.33)	0.001
Seminal vesicle invasion	2.86 (1.47-5.58)	0.002			3.07 (1.27-7.42)	0.013
Lymphovascular invasion or emboli	4.67 (2.23-9.80)	<.001			4.59 (1.71-12.28)	0.002
Perineural invasion	5.93 (2.00-17.57)	0.001			2.42 (0.75-7.86)	0.141
Apex involvement	253.23 (32.55-.)	<.001			NA
Lymph node dissection	1.05 (0.32-3.52)	0.934			0.69 (0.15-3.10)	0.631
Neurovascular bundle saving	0.55 (0.27-1.11)	0.094			0.51 (0.20-1.31)	0.165