Effect of Neoadjuvant Hormone Therapy on Resection Margin and Survival Prognoses in Locally Advanced Prostate Cancer after Prostatectomy Using Propensity-Score Matching

Table 4

Cox proportional hazards model for overall survival before and after propensity score matching.

Variables	Before propensity score matching		After propensity score matching
	Univariable analysis		Univariable analysis
	HR (95% CI)	p value	HR (95% CI)	p value
NHT plus RRP versus RRP alone	1.35 (0.52-3.51)	0.539	0.77 (0.25-2.38)	0.650
Resection margin	1.62 (0.60-4.38)	0.338	1.94 (0.63-5.98)	0.250
Age ≥65	1.27 (0.45-3.55)	0.654	1.29 (0.40-4.22)	0.669
PSA≥40	1.04 (0.39-2.77)	0.943	0.67 (0.15-3.04)	0.599
Biopsy Gleason score sum ≥7	1.36 (0.39-4.75)	0.630	0.84 (0.23-3.10)	0.795
Tumor volume ≥50%	2.17 (0.82-5.77)	0.120	3.01 (0.97-9.28)	0.056
Extracapsular extension	1.03 (0.41-2.62)	0.948	1.22 (0.41-3.65)	0.717
Seminal vesicle invasion	1.84 (0.71-4.77)	0.210	1.53 (0.48-4.86)	0.471
Lymphovascular invasion or emboli	0.45 (0.10-1.95)	0.286	0.70 (0.16-3.17)	0.644
Perineural invasion	2.69 (0.77-9.34)	0.119	2.22 (0.49-10.09)	0.301
Apex involvement	1.59 (0.51-4.94)	0.421	3.02 (0.87-10.53)	0.083
Lymph node dissection	NA		NA
Neurovascular bundle saving	0.62 (0.22-1.75)	0.370	0.69 (0.21-2.23)	0.532