UPLC-QTOF MS-Based Serum Metabolomic Profiling Analysis Reveals the Molecular Perturbations Underlying Uremic Pruritus

Table 1

Demographic description of HD patients with UP.

Parameters	LUP	HUP	value
Age, years			NS
Male/female	24/23	42/30	--
Dialysis, months			NS
Hb, g/l			<0.001
			NS
TSAT, %			NS
Fer, µg/l	128.09 (73.63–263.8)	152.58 (74.68–280.51)	NS
iPTH, pg/ml	226 (181.5–399.2)	300.7 (145.4–539)	<0.001
Calcium, mmol/L			NS
Serum albumin, g/L			NS
Creatinine, mmol/L			NS
Phosphate, mmol/L			NS
Total cholesterol, mmol/L			NS
Triglyceride, mmol/L			NS

Data are expressed as the mean ± SD or as median (first and third quartile), as appropriate.