Curcumin as a Promising Antibacterial Agent: Effects on Metabolism and Biofilm Formation in S. mutans

Figure 1

(a) Antibiofilm effects of different concentrations of curcumin and the correspondent concentrations of DMSO on S. mutans biofilm. The bacteria were inoculated in a 96-well microtiter plate containing 1% BHIS medium to form a 24 h biofilm, then washed with PBS, and incubated in 1% BHIS with different concentrations of curcumin (; ; ). After 24 h of incubation, the Colony-Forming Units (CFU) of lived bacteria in biofilm were evaluated by the MTT assay. (b) Effect of SMIC₅₀ curcumin on the growth of S. mutans.

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