Research Article

Curcumin as a Promising Antibacterial Agent: Effects on Metabolism and Biofilm Formation in S. mutans

Figure 2

Antibiofilm effect of different curcumin exposure times on S. mutans biofilm. A 24 h biofilm was incubated in curcumin at the SMIC50 for different times. The Colony-Forming Units (CFU) of lived bacteria in biofilm were evaluated by the MTT assay (a), and the percentage of biofilm biomass was evaluated by the crystal violet (CV) assay (b). The data represent the mean ± SD of three independent tests. The asterisks () indicate significant differences (, , ).