Beneficial Effects of Concentrated Growth Factors and Resveratrol on Human Osteoblasts In Vitro Treated with Bisphosphonates

Figure 7

Alizarin Red S staining on osteoblast (HOB) after 21 days of culture as IOD (Integrated Optical Density). A micrograph as an example has been reported. The cells were cultured in mineralization medium (OMM), which represents the control, and in presence of resveratrol 10 μM (R10), alendronate 5 μM (AL5), zoledronate 5 μM (ZOL5), alendronate 5 μM and resveratrol 10 μM (AL5 + R10), and zoledronate 5 μM and resveratrol 10 μM (ZOL5 + R10). Data represent means ± SE, < 0,05 and in particular < 0,05 versus OMM; < 0,05 versus OMM + R10.