Beneficial Effects of Concentrated Growth Factors and Resveratrol on Human Osteoblasts In Vitro Treated with Bisphosphonates

Table 2

Human osteoblast (HOB) treatments in complete medium (OGM) for 3 days.

Cell treatments—3 days	Evaluation performed
Complete medium (OGM)—control	MTT; ELISA for; osteoprotegerin (OPG) and bone morphogenetic protein-2 (BMP-2); immunohistochemistry for sirtuin 1 (SIRT-1) and collagen type I (Col I)
OGM + RSV 10 µM (R10)
OGM + AL 5 µM (AL5)
OGM + ZOL 5 µM (ZOL5)
OGM + AL 5 µM +RSV 10 µM (AL5 + R10)
OGM + ZOL 5 µM +RSV 10 µM (ZOL5 + R10)
OGM + CGF (CGF)
OGM + CGF + RSV 10 µM (CGF + R10)
OGM + CGF + AL 5 µM (CGF + AL5)
OGM + CGF + ZOL 5 µM (CGF + ZOL5)
OGM + CGF + RSV 10 µM + AL 5 µM (CGF + AL5 + R10)
OGM + CGF + RSV 10 µM + ZOL5 µM (CGF + ZOL5 + R10)