Research Article

Alkaline Phosphatase Kinetics Predict Metastasis among Prostate Cancer Patients Who Experience Relapse following Radical Prostatectomy

Table 1

Descriptive characteristics of study sample (n=701).

Study Cohort (N=701)

Continuous VariablesMean ± SD

Age at CaP Diagnosis (years), Mean ± SD62.6 ± 6.4
Age at RP (years), Mean ± SD62.8 ± 6.4
Time from RP to Distant Metastasis (years), Mean ± SD10.1 ± 4.7

Categorical VariablesN ()

Distant Metastasis, N ()63 (9.0)
Neo- and/or Adjuvant Treatments Received, N ()127 (18.1)
Salvage Treatments Received, N ()437 (62.3)
PSA Doubling Time (Months), N ()
 Missing22 (3.1)
 <10129 (18.4)
 ≥ 10550 (78.5)
D’Amico risk stratum, N ()
 Missing165 (23.5)
 Low171 (24.4)
 Intermediate199 (28.4)
 High166 (23.7)
Race, N ()
 Missing8 (1.1)
 African American163 (23.3)
 Caucasian494 (70.5)
 Other36 (5.1)
PSA at CaP Diagnosis, N ()
 Missing126 (18.0)
 <10371 (52.9)
 10-20139 (19.8)
 >2065 (9.3)
Pathologic Gleason Sum, N ()
 Missing98 (14.0)
 ≤6234 (33.3)
 3+4201 (28.7)
 4+373 (10.4)
 ≥ 895 (13.6)
Pathological T stage, N ()
 Missing15 (2.1)
 T2334 (47.6)
 T3-T4352 (50.3)
Positive Surgical Margin Status, N ()311 (44.4)
Positive Extracapsular Extension, N ()265 (37.8)
Positive Seminal Vesicle Invasion, N ()96 (13.7)