MicroRNA-219-5p Promotes Tumor Growth and Metastasis of Hepatocellular Carcinoma by Regulating Cadherin 1

Table 3

Univariate and multivariate analyses of factors associated with recurrence in patients with hepatocellular carcinoma (HCC).

Features	Recurrence
	Univariate	Multivariate
		HR	95% CI
Sex				NA
Male versus female	0.331			NA
Age				NA
>50 versus ≤50	0.832			NA
HBsAg				NA
Positive versus negative	0.043	0.761	0.392~1.476	0.419
AFP				NA
20 ng/ml versus ≤20 ng/ml	0.615			NA
Liver cirrhosis				NA
Yes versus no	0.065			NA
Tumor size				NA
>5 cm versus ≤5 cm	<0.001	1.744	1.274~2.388	<0.001
Tumor encapsulation				NA
Yes versus no	0.671			NA
Tumor number				NA
Multiple versus single	0.010	1.579	0.751~3.318	0.228
Vascular invasion				NA
Yes versus no	0.014	1.870	1.205~2.902	0.005
Tumor differentiation				NA
I~II versus III~IV	0.539			NA
miR-219-5p				NA
High versus low	0.014	1.663	1.072~2.577	0.023

Abbreviations. HBsAg: hepatitis B surface antigen; HR: hazard ratio; CI: confidence interval.