Potassium Channel Activation Is Involved in the Cardiovascular Effects Induced by Freeze Dried Syzygium jambolanum (Lam.) DC Fruit Juice

Figure 8

Effect of JSJ on potassium currents in mesenteric smooth muscle cells. (a) Representative IK recordings before (control) and after JSJ perfusion at 500 μg/mL and 1000 μg/mL. Currents were elicited by depolarizing pulses to +60 mV at 200 ms duration from a holding potential of -60 mV. (b) Bar plot showing statistical analysis obtained from the maximum value of current efflux (pA/pF) at each differing JSJ concentration. Control was absent of JSJ perfusion. (c) Representative recordings of IK total acquired without JSJ incubation. (d) IK recordings displayed for JSJ at 1000 μg/mL. The recordings were obtained by triggering depolarizing pulses from -60 mV to + 60 mV in 10 mV steps. The holding potential was set at -60 mV. (e) I-V relationship of IK total in the absence (open circles) or presence (filled circles) of 1000 μg/mL JSJ perfusion. Results represent the mean ± SEM; (n=7; p<0.05; p<0.01).

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