Magnitude of Neural Tube Defects and Associated Risk Factors at Three Teaching Hospitals in Addis Ababa, Ethiopia

Table 5

Logistic regression analysis on determinants of neural tube defects, Addis Ababa University Teaching Hospitals, Ethiopia, 2016 .

Variables	Neural tube defects		value	OR (95% CI)
	Yes	No		COR	AOR
Annual family cash income (USD)			0.032
<1300	29	49		2.2 (1.13–4.35)	2.50 (1.21–5.52)
1300–1800	35	55		2.39 (1.25–4.57)	2.82 (1.33–5.81)
1801–2700	27	43		2.36 (1.18–4.69)	2.64 (1.21–5.82)
>2700	20	75		1	1
Drugs in the 1st trimester			0.001
Folic acid/multivitamins	15	68		0.39 (0.28–0.73)	0.47 (0.23–0.95)
Any other drugs	22	23		1.69 (0.88–3.25)	2.12 (0.98–4.56)
None	74	131		1	1
Prepregnancy BMI			0.043
<24.9	85	190		0.55 (0.31–0.98)	0.49 (0.29–0.95)
≥25	26	32		1	1
Place of ANC			0.022
Private clinic/hospital	10	17		1.77 (0.16–19.3)	8.34 (0.57–121.3)
Health center	93	158		1.77 (0.18–17.2)	4.76 (0.41–55.67)
Public hospitals	7	44		0.48 (0.04–5.26)	1.68 (0.12–22.75)
No ANC	1	3		1	1
END history			0.042
Yes	7	4		3.67 (1.05–12.80)	4.15 (0.95–18.16)
No	104	218		1	1
Contraceptive use before conception
Yes	55	133		0.66 (0.42–1.04)	0.67 (0.40–1.12)
No	56	89		1	1
Outcome (sex)			0.075
Male	52	127		0.66 (0.42–1.04)	0.56 (0.33–0.94)
Female	59	95		1	1
Pregnancy type			0.077
Planned	84	186		0.60 (0.34–1.06)	0.47 (0.24–0.92)
Unplanned	27	36		1	1
Remember LNMP			0.109
Yes	77	134		1.49 (0.92–2.41)	1.96 (0.98–3.40)
No	34	88		1	1
Preconception care			0.016
Yes	11	46		0.42 (0.21–0.85)	0.50 (0.21–1.21)
No	100	176		1	1

END: early neonatal death; BMI: body mass index; ANC: antenatal care; LNMP: last normal menstrual period.