Costus afer Protects Cardio-, Hepato-, and Reno-Antioxidant Status in Streptozotocin-Intoxicated Wistar Rats

Figure 3

Histological examination of sections from the kidneys of experimental animals after 60 days of administration of the hydroethanolic leaf extract of C. afer showing abnormal architecture (b) compared to normal group (a). TCP: proximal tube; TCD: distal tube; G: glomerular; CT: tubular clarification; I: glomerulosclerosis; VC: vascular congestion. (a) Normal control; (b) diabetic control; (c) diabetic treated with 250 mg/kg of C. afer; (d) diabetic treated with 500 mg/kg of C. afer; (e) diabetic treated with 1000 mg/kg of C. afer; (f) diabetic treated with 250 mg/kg of metformin.

(a)

(b)

(c)

(d)

(e)

(f)