Increased Autophagy Enhances the Resistance to Tumor Necrosis Factor-Alpha Treatment in Rheumatoid Arthritis Human Fibroblast-Like Synovial Cell

Figure 6

Cells were treated in the presence or absence of d 5 mM 3-MA for 48 h. Autophagy was detected by western blot (LC3-II) and cell apoptosis was determined by flow cytometry. The correlation between autophagy and apoptosis was analyzed with Pearson correlation in RA-HFLS (a) and in HFLS (b).

(a)

(b)