Clinical, Histological, and Immunohistochemical Findings in Inclusion Body Myositis

Figure 3

Immunohistochemical findings in muscle biopsy of patients with sIBM. (a) Presence of areas of positive staining for CD8-lymphocytes (case 2). (b) Diffuse increase of histocompatibility antigen type I expression (case 2). (c) Increased LC3 expression in the vacuole (arrow) (case 5(b)). (d) Increased alpha-synuclein expression in the vacuoles (arrows) (case 5(b)). (e) Increased TDP-43 expression in the vacuoles (arrows) (case 5(b)). (f) Increased p62 expression in the vacuoles (arrows) (case 5(b)).

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